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Jeremy Frank & Associates

Jeremy Frank & Associates

Therapy for Addiction & Mental Health

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    • Carla Runnels, LPC, CAADC, MA
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    • Alexander Ott, MA, LMFT
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Xylazine in Heroin: What You Need to Know

Reports from cities across the U.S. show that xylazine-laced heroin, sometimes called “tranq dope,” is becoming more common.

The landscape of substance use is constantly shifting. In recent years, one troubling development has been the appearance of xylazine—often called “tranq”—mixed into heroin and other street opioids. This combination is creating a dangerous new chapter in the opioid crisis.

What Is Xylazine?

Xylazine is a veterinary sedative, not approved for human use. Dealers often mix it with heroin or fentanyl because it increases the drug’s effects and makes it stretch further. However, its impact on people can be devastating.

Why Is It Dangerous?

Xylazine is not an opioid, which means naloxone (Narcan) does not reverse its effects. This makes overdoses involving heroin cut with xylazine especially risky. Some of the most concerning dangers include:

  • Severe sedation leading to slowed breathing and unconsciousness.
  • Risk of overdose that is harder to reverse.
  • Serious skin wounds and ulcers, sometimes requiring medical treatment or even amputation.
  • Increased physical dependence, making withdrawal more complicated.

The Growing Presence of “Tranq Dope”

Reports from cities across the U.S. show that xylazine-laced heroin, sometimes called “tranq dope,” is becoming more common. It’s cheap, potent, and unpredictable. This trend has raised alarms among public health experts and addiction treatment providers alike.

What People Need to Know

If you or someone you love is using heroin, it’s important to understand the risks associated with xylazine:

  • Check your supply: While test strips exist for fentanyl, there are currently no widespread test strips for xylazine.
  • Carry naloxone: Even though naloxone won’t reverse xylazine, it can reverse the opioid component of an overdose. It’s still life-saving.
  • Seek medical care for wounds early: Skin injuries linked to xylazine can worsen quickly.
  • Don’t use alone: Having someone nearby could save a life in case of overdose.

Hope and Healing Are Possible

The rise of xylazine in heroin is frightening, but recovery is still possible. Therapy, medical support, and community resources can help people find stability and healing. At our practice, we specialize in supporting people navigating addiction, meeting them with compassion and real strategies for change.


Contact Us for Help

If you or someone you care about is struggling with heroin use or worried about xylazine, we’re here. Reach out today to start a conversation about treatment and recovery.

September 8, 2025 by Jeremy Frank and Associates
Category: Addiction Recovery, Addiction Treatment, Harm Reduction, Mental Health, ResourcesTag: addiction counseling, drug recovery, substance use

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Jeremy Frank & Associates
About
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    Philadelphia, PA 19130

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    Bala Cynwyd, PA 19004

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Information on this website www.jeremyfrankassociates.com does not constitute a therapeutic relationship and should not be construed as clinical advice, counseling or therapy. We assume no liability for the information within this website or harm that may result from using, referencing, relying on, or decisions executed from its use. 

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